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Central neural control pathways directed to brown, white, and transformed "Beige" fat

thesis
posted on 02.08.2017 by NICOLE MAREE WIEDMANN
The functional recruitment of brown and inducible “beige” fat is, primarily dependent on an intact sympathetic neural input, with little insight into the neural control of beige adipose tissue. Here we demonstrate that after induction of beige adipocytes in white fat after cold exposure there is a functional reorganisation of supraspinal pathways. Furthermore, the neurochemical profile of sympathetic ganglia projecting to beige fat becomes more alike the profile of those projecting to brown fat. The findings of this thesis significantly build upon our understanding of the neuroanatomical and neurochemical blueprint of pathways directed to brown, white, and transformed beige fat.

History

Principal supervisor

Brian Oldfield

Additional supervisor 1

Aneta Stefanidis

Year of Award

2017

Department, School or Centre

Physiology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

Doctorate

Faculty

Faculty of Medicine Nursing and Health Sciences

Exports

Exports