Brainstem and Cerebellar Volume Loss in Progressive Supranuclear Palsy

Progressive Supranuclear Palsy is a neurodegenerative disorder with variable distributions of related pathology in the brain, frequently implicating the cerebellum, however the patterns of corresponding volume loss on structural imaging remains equivocal. This thesis examines the brainstem and cerebellar patterns of volume loss over time in this disease, highlighting extensive involvement of these structures with a distinct spatiotemporal profile.