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Bioprospecting of Streptomyces species derived from mangrove soil in Malaysia for anti-Methicillin-resistant Staphylococcus aureus activity

thesis
posted on 07.12.2020, 04:17 authored by HEFA MANGZIRA KEMUNG
Streptomyces are a group of bacteria known for their contribution to medically important drugs including the antibiotics. The work presented in this thesis, focuses on identifying Streptomyces bacteria collected from the less explored mangrove forest soils in Malaysia as sources of future antibiotics. Among the Streptomyces assessed, Streptomyces sp. strain MUSC 125 stands out as a promising candidate. The study shows biologically active compounds of Streptomyces sp. strain MUSC 125 as capable of stopping the growth of Methicillin-resistant Staphylococcus aureus, one of the disease-causing bacteria for which limited treatment options remain to date.

History

Campus location

Malaysia

Principal supervisor

Goh Bey Hing

Additional supervisor 1

Dr. Lee Learn-Han

Year of Award

2020

Department, School or Centre

School of Pharmacy (Malaysia)

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Pharmacy and Pharmaceutical Sciences