Monash University
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Reason: Under embargo until 4 February 2025. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

Bio-nano studies of organosilica and immune cells in vitro and in vivo

thesis
posted on 2024-02-03, 23:36 authored by EDWARD CHARLES HENDERSON
Nanoparticle-based nanomedicines have seen an increase in their clinical presence in the modern era, however much of the knowledge underpinning the mechanisms and interactions of these materials in biological environments is still in development. In this thesis, organosilica nanoparticles were synthesised and functionalised to investigate their bio-nano interactions with in vitro immune cell cultures as well as in a syngeneic ovarian cancer murine model

History

Campus location

Australia

Principal supervisor

Simon Corrie

Additional supervisor 1

Magdalena Plebanski

Additional supervisor 2

Kirsty Wilson

Year of Award

2024

Department, School or Centre

Chemical & Biological Engineering

Additional Institution or Organisation

Royal Melbourne Institute of Technology

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Engineering