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Assessment of Coronary Inflammation Using Novel CCTA Marker Pericoronary Adipose Tissue (PCAT) Attenuation

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posted on 2022-04-21, 23:22 authored by JEREMY ARJUN YUVARAJ
Coronary artery disease is a leading cause of death in which chronic vascular inflammation plays an important role. Pericoronary adipose tissue (PCAT) is a fat depot beside the coronary arteries that undergoes distinct changes in response to vascular inflammation. These changes can be mapped as radiodensity or attenuation using non-invasive coronary computed tomography angiography (CCTA) imaging, and provides a specific means of assessing inflammation in the coronary vessels. PCAT attenuation therefore presents a potential means of determining inflammatory risk in a range of coronary and metabolic disease states.

History

Principal supervisor

Dennis Thiam Leong Wong

Additional supervisor 1

Nitesh Nerlekar

Additional supervisor 2

Stephen Nicholls

Year of Award

2022

Department, School or Centre

Clinical Sciences at Monash Health

Additional Institution or Organisation

Medicine

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences