Approaches towards drug detection using porous silicon-based mass spectrometry

With the changing landscape of drug use, there is a continued major interest in the ability to accurately and sensitively detect such compounds directly from biological fluids in different contexts. This thesis aims to meet the challenges of drug detection using porous silicon-based laser desorption/ionisation mass spectrometry, an alternative analytical technique. The research performed in this thesis has transformed and progressed the analytical approach towards real world applications in the areas of drug detection and monitoring.