Monash University

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Reason: Under embargo until March 2020. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

An investigation into the contribution of B cell activating factor, antibodies and complement in the pro-hypertensive actions of B cells

posted on 2019-03-15, 01:41 authored by MAGGIE LIEU
High blood pressure is a major cause of heart disease. Strikingly, many patients with this disease are not treated effectively by current blood pressure lowering drugs, highlighting the need to find more effective therapies to treat this disease. Research in our group has shown that B cells, a major cell type of the immune system is important in this disease. This thesis examines the role of key proteins of the immune system in switching on B cells during this disease (B cell activating factor) or are ways by which B cells could contribute to high blood pressure (antibodies and complement).


Principal supervisor

Grant Drummond

Year of Award


Department, School or Centre

Biomedical Sciences (Monash Biomedicine Discovery Institute)

Additional Institution or Organisation


Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences