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Reason: Under embargo until October 2023. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library
An Integrated Systems Biology Approach to the Discovery and Characterisation of Novel Regulators of Hepatic Lipid Metabolism
thesis
posted on 2020-10-30, 00:38 authored by MICHAEL FITZGERALD KEATINGThe epidemic of obesity worldwide has contributed to the meteoric rise in the chronic metabolic disorders such as fatty liver disease and cardiovascular disease. Underlying these chronic conditions is a disruption to the metabolism of fat, which predominately occurs in the liver. Given this, the research focus of this thesis was to identify new proteins and pathways that have the potential to be targeted by drug therapy, or act as biomarkers of metabolic disease, through a cutting-edge discovery platform.
