Reason: Under embargo until 28 April 2025. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library
Affinity Labels of the Renin-Angiotensin System
thesis
posted on 2024-04-27, 23:09authored byIVAN MASLOV
This thesis aims to comprehensively explore ligand-based approaches of the Renin-Angiotensin System, with a particular focus on ACE2 and AT2R, in order to advance our understanding of their roles in health and disease. The study's diverse methodologies encompass covalent binding strategies, radioligand binding assays and fluorescent microscopy techniques. The ultimate goal is to contribute valuable insights into the intricate RAS, paving the way for novel therapeutic strategies and expanding ligand-based approaches in GPCR research.