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Adenosine A2B Receptor Pharmacology and its Role in Pathophysiology

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thesis
posted on 14.08.2017 by ELIZABETH ANN VECCHIO
The adenosine A2B receptor is an important but poorly understood drug target. This thesis investigated new paradigms of adenosine A2B receptor signalling and behaviour and identified drugs that could selectively promote beneficial outcomes in prostate cancer cells and cardiac fibroblasts. This information helps to inform how targeting the adenosine A2B receptor may be used as a treatment for prostate cancer and cardiovascular disease.

History

Campus location

Australia

Principal supervisor

Lauren Therese May

Additional supervisor 1

Paul White

Year of Award

2017

Department, School or Centre

Drug Discovery Biology

Course

Doctor of Philosophy

Degree Type

Doctorate

Faculty

Faculty of Pharmacy and Pharmaceutical Sciences

Exports

Categories

Exports