A biochemical characterisation of the MACPF/CDC pore assembly
thesisposted on 12.03.2019 by BRADLEY ALAN SPICER
In order to distinguish essays and pre-prints from academic theses, we have a separate category. These are often much longer text based documents than a paper.
The blood plasma contains vital immune proteins for defending against bacteria. This thesis determines high-resolution structures of a giant pore forming protein in the plasma called the Membrane Attack Complex (MAC). Furthermore, a biochemical examination provides a mechanism of how MAC proteins assemble, and an improved understanding of the immune system.