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A biochemical characterisation of the MACPF/CDC pore assembly

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thesis
posted on 12.03.2019 by BRADLEY ALAN SPICER
The blood plasma contains vital immune proteins for defending against bacteria. This thesis determines high-resolution structures of a giant pore forming protein in the plasma called the Membrane Attack Complex (MAC). Furthermore, a biochemical examination provides a mechanism of how MAC proteins assemble, and an improved understanding of the immune system.

History

Principal supervisor

Michelle Anne Dunstone

Year of Award

2019

Department, School or Centre

Biochemistry and Molecular Biology

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine Nursing and Health Sciences

Exports

Categories

Exports