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A Synergistic Approach to Antimicrobial Synthesis
thesis
posted on 2021-01-11, 03:58authored byLydia Scott
This thesis outlines two key approaches to antimicrobial synthesis. The first is through the attempts at the synthesis of analogues of a known antibiotic, virginiamycin MII. The second is through reaction design targeted towards a natural product with antimicrobial activity, hisunic acid. The reaction design revolves around the application of organocatalysis, specifically N-heterocyclic carbenes.