4D Image-Guided Linac Based Stereotactic Body Radiotherapy Treatment for Primary Renal Cell Carcinoma

In Australia, kidney cancer is considered the 9th most common cancer. The standard of care for managing kidney cancer is surgery or similarly invasive, thermal-ablative procedures. Stereotactic body radiotherapy (SBRT) can be used as a non-invasive modality to treat kidney cancers using high-dose, high-precision radiation. This thesis demonstrates the safe and practical use of SBRT. The themes explored include minimising kidney motion for treatment, computer-modeling the radiation in the body to minimise treatment-related toxicities, and directly before treatment, accurately guiding the radiation to the tumour.