Method for detecting rheumatoid arthritis employing the CB10 peptide of mammalian type II collagen as an antigen
standardposted on 07.09.2016 by Andrew Cook, Merrill Rowley, Ian Mckay, Montech Medical Developments Pty Ltd, Rondole Pty Ltd
A formal and detailed description of an invention, protocol or workflow; examples include patents, patent applications and requests for comments (RFC).
A predictive test for rheumatoid arthritis comprises the detection of antibodies to collagen in a biological sample from a patient by contacting the biological sample with an antigen comprising the CB10 peptide of mammalian type II collagen, or an antibody-binding fragment or variant thereof, for a time and under conditions for an antibody-antigen complex to form, and detecting the antibody-antigen complex, for example by immunoassay. A diagnostic test kit is also disclosed.