monash2726JP_3510889.pdf (634.4 kB)
Tōnyōbyō oyobi zentōnyō shōjyō no shindan no tameno hōhō
Version 2 2016-09-14, 06:42
Version 1 2016-09-07, 23:38
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posted on 2016-09-14, 06:42 authored by Ian Ray Mckay, Merrill Joy Rowley, Pau Zev ZimmetEnglish title: Methods for the diagnosis of diabetes and prediabetic conditions
A method for detecting autoantibodies to glutamic acid decarboxylase (GAD) in the serum of a patient as diagnostic of a diabetic or prediabetic condition in the patient, comprises contacting a serum sample from the patient with a GAD antigen and detecting binding of autoantibodies to GAD in the sample by the GAD antigen, wherein the GAD antigen comprises a GAD preparation containing an enhanced amount of dimer(s) or oligomer(s) of the 65 kD or 67 kD isoforms, or both, of GAD. A diagnostic kit is also inclosed. [Abstract from Spanish version of this patent]
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