Microtubule filament curvature induced by antimitotic drug colcemid, revealed by single-molecule super-resolution microscopy

HeLa cells drugged with antimitotic colcemid for 5 hours, fixed, fluorescently labelled for tubulin with Alexa Fluor 647, and imaged using single-molecule localization microscopy method dSTORM. Images rendered at 20 nm/pixel.