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20170419-Carron-Thesis.pdf (14.64 MB)

Investigating the changes in Inhibitory Neurons following two different models of Traumatic Brain Injury

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thesis
posted on 2017-11-20, 03:56 authored by Simone Francina Carron
Different forms of Traumatic brain injury (TBI) disrupt brain excitation/inhibition balance. This thesis examined changes in brain inhibition following two different types of brain injury and its consequences on behaviour. A key finding of this thesis is that particular forms of inhibition are altered after trauma confirming that susceptibility of brain inhibitory cells to trauma is brain area specific, injury type and time dependent. These findings have important implications for evaluation of new treatments for brain injury by targetting particular subsets of brain inhibitory cells as a function of injury type and time.

History

Principal supervisor

Ramesh Rajan

Additional supervisor 1

Edwin Yan

Additional supervisor 2

Arthur Lowery

Year of Award

2017

Department, School or Centre

Biomedical Sciences (Monash Biomedicine Discovery Institute)

Additional Institution or Organisation

Physiology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine Nursing and Health Sciences

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    Faculty of Medicine, Nursing and Health Sciences Theses

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