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Reason: Under embargo until February 2021. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library
Development of recombinant multiepitope proteins-based point of care test diagnosis for multiple sexual transmitted diseases in humans
thesis
posted on 2020-02-11, 12:31 authored by RAGUL PARAMASIVAMThis research aims to performed systematic review to assess the diagnostic accuracy of all reported recombinant antigens and multiple point-of-care rapid assay platforms for Chlamydia, Gonorrhea, Syphilis, Herpes, Acquired Immune Deficiency Syndrome and Hepatitis B detection according to standard methods and summarise test performance using meta-analysis to identify promising antigen for development of multiepitopic peptide for detection of Chlamydia, Gonorrhea, Syphilis, Herpes, Acquired Immune Deficiency Syndrome and Hepatitis B antigen and antibodies. Further to develop indirect IgG and IgM ELISA, Lateral flow rapid assay and IgM and IgG piezoelectric QCM diagnostic assay to detect STIs antibodies using multiepitopic peptides (MEP).
History
Campus location
MalaysiaPrincipal supervisor
Pushpamalar JanarthananAdditional supervisor 1
Prof. Sunil K LalAdditional supervisor 2
Prof. Dhinakarraj GopalAdditional supervisor 3
Prof. Saravanan MuthupandianYear of Award
2020Department, School or Centre
School of Sciences (Monash University Malaysia)Course
Doctor of PhilosophyDegree Type
DOCTORATEFaculty
Faculty of ScienceUsage metrics
Categories
Keywords
Sexually Transmitted DiseasesHIVAIDSSyphilisHerpesgonorrheaChlamydiaHepatitis BAssay DevelopmentSerologicalEthiopiaProteins and PeptidesMedical Biotechnology Diagnostics (incl. Biosensors)Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies)Immunological and Bioassay Methods
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