ONG, KUAN SHION Identification and Characterization of Pyochelin Produced by a Novel Bacterium Burkholderia paludis The increase in prevalence of antimicrobial-resistant bacteria in the past decade is a serious global threat, hence there is a need for new antimicrobial compounds to treat bacterial infections. One strategy to look for antimicrobial compounds is by prospecting for novel microorganisms. This thesis characterizes a novel bacterium, Burkholderia paludis along with its antimicrobial compound which is pyochelin. Pyochelin is able to inhibit the growth of antimicrobial-resistant bacteria by enhancing the generation of free radicals. This finding reveals a new function of pyochelin and signifies a promising alternative to treat infections caused by antimicrobial-resistant bacteria. Antimicrobial;Burkholderia;pyochelin;tropical peat swamp forest;Microbiology 2018-01-04
    https://bridges.monash.edu/articles/thesis/Identification_and_Characterization_of_Pyochelin_Produced_by_a_Novel_Bacterium_Burkholderia_paludis/5746215
10.4225/03/5a4db3de150ef