ELLIS, DARCY PAUL The role of NF-kappaB transcription factors in Virtual Memory (Tvm) CD8+ T cells This thesis investigates the influence of the NF-kappaB transcription factors in a subset of CD8+ T cells, termed virtual memory cells. Virtual memory cells are T cells that have become activated and acquired enhanced immune functions through mechanisms that normally act to maintain homeostasis of the immune system. NF-kappaB transcription factors are a collection of proteins that function to turn on and off genes. This investigation shows that a member of the NF-kappaB family, RelA, plays an important role in regulating genes in virtual memory cells that are important for their development, function and homeostatic maintenance. Virtual Memory cells;NF-kappaB;RelA;CD8 T cells;Cell Biology;Biochemistry;Immunology 2020-02-26
    https://bridges.monash.edu/articles/thesis/The_role_of_NF-kappaB_transcription_factors_in_Virtual_Memory_Tvm_CD8_T_cells/11900310
10.26180/5e55b67d767f5